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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8760378628caecac0579f435314eeddf74ba59e3d0eb869913b50ad1911d2887' 
  AND token = 'p8bOtWUtWXLsYuaKb++EukCNxWcZjwkKUrv0h2x/N+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}