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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c433a295a826067183c8bb9fd8e1820e6d897c263c7d23ea5776d99c153dcfb4' 
  AND token = 'pwteEFkdOZQbcEK/gGdaWZ8BP4GVyhP0sSaUwM8UikM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}