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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4894c9f315b1d37452ed31a86d23d40e830a5ed7feea6df597938f331e6769d3' 
  AND token = 'NHPx2/YVm6e870dGtiIAtAFBd5N+o4cezwBgVV1h1hQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}