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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64845d7f646828fd72f4d5d032c3504cce4dec5dfff404f9bf3bcd4572a0fd6c' 
  AND token = 'Hgsn8tJC4/Kh+X0FU+nTTysGxu9nMwrM22r7UDU+dRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}