SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fe8fcee9e4ef0728fbfd4ad9d9e31508c18c531624965d71e1fc9154cdb5425' 
  AND token = 'RAZlDgj8FZB8elYHAyB9K4R+mT0ap0cJll/M2ko1D70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}