SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '750fa6749dbb77bca97159b56dac2ce97af77330c556976041425c17e210c0fc' 
  AND token = 'kFZcfxsn1wYg6OTa+JbU7c+zDqhMi+Ru3m6QuITHAU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}