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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74f43bd4b54a09d5393cac1badc1486e04849a4286a22cad681e847bb08f8ff3' 
  AND token = 'MYFhH8vFxPf3V4KDj4ovMh0HjqpeI1Ih6E+vurJnlPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}