SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16620005282d01814f950b6d61589ff6f9e15854c2a205829411f2a63d31e28b' 
  AND token = 'lIHU1UFnufoz73MpADtOD/1de/0dkJlj5iuk2YgpzEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}