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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc440ecc7a0b13d4527b42c8e326e23187909b83651e39199e3539646af69e53' 
  AND token = 'gcoOY0cL6mbJw1qw51GvCgrr5QXnuSCRO1kqT6d7GT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}