SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3454544f2e42ef5e232186962bebb4bd1aa8829e91efd8c29b484afb8c6afa3' 
  AND token = 'ah3WR/0N10wDEnHkdbGnbVooQ70igNxtbdv9Y9Yo4kA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}