SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1598daa18b59e1c6c8a46bb719c8407229d8aba85d8af12c439d6f0916262f0' 
  AND token = 'dmE9XV/Z3uz8inGfYuUSZsYcQSFAjda7C09pcL3zSBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}