SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c0606e31d8a59af8642f2fed7c80048329fba3753469da4c84e27a369105c03' 
  AND token = 'hxIqXt7/qmwasOhMjmn+44UJ3QeZB0HFNcpzuh10dA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}