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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc72ef077b643431d4c09eb9ef8e8ed99c6a994741d26e695fc9de110dba3299' 
  AND token = 'm+0rVo9p+Cpeg8Ush0Y664I4iExkcw0bQAkPI7vOkpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}