SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e21869ce38aa87ed8bea075eaa7fda3fd010d84e25e0ced10ef7167999c840ac' 
  AND token = '2UrbJM2O7y7jTLBXredc7MZZBBk/vTxPgMUrsi7paaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}