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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03e7a8db96ba6c23eb50c8669e8f3b460ec70539f6621ce3eef0b9871a9621a5' 
  AND token = '1Yjy2l21oMdqOZBwZ5jYbfWL2zgIm0yDIfy/rabP+Eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}