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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ab63bea30629a539e0bdc6616de00d3b4f28721f79487e64d542e2e61f1b65c' 
  AND token = 'qMAdjOXTOODv1GEIRNhk+XiCnK1C6LMnzkFhnD58cXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}