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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f8c6ee6e6710ab1e5d3d4984ebbd362d6a53db9f4af108e37ae9a22e4790d6' 
  AND token = 'Z6GmpEKFll1ZZH8N/OssTyUdFxeEF8BiRtgIueOFc3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}