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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2106b7eec397955b062883fa896b22035ce81801e8c6445d767b8a541e7b4ce3' 
  AND token = 'xxmTLogdP6dvSXgAloOVCCqEaJkSpI2OE9NL1WwLwEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}