SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1e5393f281e63655c92180ceeae6cfc947d0f32cfa427ab4a903cab1fe8faff' 
  AND token = 'DquqknOv1ceS4lAd6Ds2QiO4lnfuQXZUpPEit0udDoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}