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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ddba14b7789076a14b1b75cd0b44a2f964d590a6618a1f4f727d6302c4ad38a' 
  AND token = 'F8POu5Pox8Q7EVYvofK0i1yc3WlOta7ssXzavW1KM6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}