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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d6046def596bba121459f94fb1da3bf6c2e2681d0440ec49cab9d14dfd276d3' 
  AND token = 'it3PhRTu3ROopk873T9OnhmkfkCHKNiGBrMs66FWFUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}