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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bcf3eb8a953c722bb57509cc72b677d053b65868258e2b279f77035e00cbd706' 
  AND token = 'qu4eIeShR0O6+0zUjPwbZr9QqI0fDcjvCp3OBPMUe3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}