SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59b89ed4f149964ab71ec73d3524871bee5058068edb458f9ed025b4b293b852' 
  AND token = 'DtyR++jYUpAa89sR8UyO2AQT7O5k+L47oNZN8P9XHDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}