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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fe6f42d06f92b22fd11a925a6b03b9590eef334609402bb37e47244d5056236' 
  AND token = 'LWKzR2ikGnduZsXIpwo3A3cxtgQgv2u5ilWiScJqERA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}