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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4206b0057685226250b382f152d2da4153e2df3a18bce9f6e6f62fc0af6b88e4' 
  AND token = 'FhZgrDr0t+R0hGduduaZTRyEsQ05oZ6He4sP4tyCXxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}