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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e9806dce677582cc1e103250e0166b081a294a5359dddf7085b7da61d6e60a5' 
  AND token = 'AfmPFZEVKpBVHw86Pu85fHSg6oP9hOiI25F4LnTM5hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}