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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e4e3e5cbd3da75d6eab464790eab860eb95666bbf53246b68b2733f8a77d9ec' 
  AND token = 'qh8z1Lo33TTbEQeWzgG7oA5fRaeHSSZaYeO779JgIxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}