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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a9b05b63e57c9f05c63bed62d4dd8bf1a9d55b315ea540f234cd96e362c9443' 
  AND token = 'N8TrFtPZvOO6G8GasHWDg6l9va74ZgRRNtVghHcVTws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}