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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1657596aea2632aab4813cfa50fa8bb21e7145f3d8ea217fb4d0202429a23f32' 
  AND token = '9rkTCsmPKtZkX2wLi1LqiCWEUwaZSkcftrE4PY1m2yQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}