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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e21c95655e4ee0ab57cead7ca16f151ebec60088c86a675f784b6d5a3e44da3d' 
  AND token = 'iKznfgH2nDJfdsXvon7V1XZhurZ3SWR3xZqeiOlNdQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}