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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f1b87d9520eb9d3c53576ede805ddc7bf6893cc86c9f478a3565a27b0e04af1' 
  AND token = 'RwVbH99ND6JqNoS+8DR1UiQVIWF762Ebfcs3sgVmvzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}