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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7ec2f4e2f617124a71eb42aa7438bce1b8ec6fd1c2b595c7f60e691b475f091' 
  AND token = 'C9OxCixd8b0wEl7S+DwrdL6HqL9StC9LZYf/i65XGhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}