SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5ef56efdb850c9fbd8eed8d2489e1104a28886128256651d287c081c8881093' 
  AND token = 'ovEMr2ZC+sXLRlnEW+cuVSZgUbYgygaIn0HsG8E0kDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}