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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e29910ac9ee7386fb5a4cab4c42f86ac03f4325b7732f36f2f63b04a7f594f4' 
  AND token = 'm4xoKD0XaAbLUCCR4EKcMHgZ1G+Ts97u2FOPd9eUtK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}