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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae0262d210d4e1c4c07e93638db79c6ae0aa3215065e1a6d8bb78383b0d13955' 
  AND token = 'CoJ7BFM6Rd1dJnRz7Yh1sY7emMisWdlWHI5wxsgbKm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}