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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fce7698bc12e8df2cefc058805b35162cef35b43b9cdc7f60952ffcbc05f402' 
  AND token = 'd4kGTsBkApxTlNytdMwUxUvcxyqEftjf3Pn/VkW1Xm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}