SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '560361314246a9a34485f02c125b9fb24fc00f1a9c03297015c86007d72fc010' 
  AND token = 'kIqfzURYeanRFyi19HvFRIFHv+wsbBPEoDRRcOAomGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}