SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f85d14f8c301baf33de651a35f30976b56b3c1c13df539f2d022fa0864e7010' 
  AND token = 'l5xDwBJ803nkyASN3GLMx6tXv1WP45GhBZgseikDDGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}