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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b6cc50b79838c13536a5521bf880d8c2b476fcd1634a64b38a3e2f12102a32c' 
  AND token = '3d67Dqt5WB03/YrSPm3DY46e2j0Qu+QsCD8N3Y8o7gM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}