SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '917ba8d2b626878164bbd6132586684a81a66b57dde283b03b93e12a63c99e7c' 
  AND token = 'VTusHGeUqM/1ZpblXwi4sBvmTec3sB7ohrnD/6Pq2Z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}