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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8689abc8d07032faa8665e4d3a60e47fe02402d159826ea1012aeabc56fe2918' 
  AND token = 'gbeQgG2yY05LT5Wy+hc6I3P/p4M5D+oDW9Fc/PMgJB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}