SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9824d5f65d3ea391d09d029a644ce8704e1c28e1aa8c270527cd9423e754c57' 
  AND token = 'sanUynbb9kyOUzZxCjt+58o064NnvzQ6iGuvjNm2xd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}