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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c07e80e060518229aa5e9354b8735e16fd2a604dcbcc6ee5a61234644375018c' 
  AND token = 'N/U1bNKJBpkEojBYjr2Tak4LMJyHoxrvaIFq06hJvnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}