SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed76572f1b79a90a489abb255bf45fd4c3e8ef9f37e529578517cd6e069fb31a' 
  AND token = 'dVccaeB7eGWk5R2ZFFRzmNOqXvlAXZS5R5eehvkfzHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}