SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fca0eded633ea88191bafdc233b8c314ec54f6e49ffd37f54a31820156650a33' 
  AND token = '3dNZuJQSd+ndTfidjwJ1GQyflDIwxVsz0R2CEkiuvqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}