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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f10d3725398a2730dbff6ac950c1ab96f69c409d347151438e6c50e04af863ed' 
  AND token = 'FE9vOL8CznUyTb8YTnWR1r+UAC2WpO0DhbzOuMxk+i4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}