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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17a2e32fc9628062d572dc2ff42d45ba2ed1b10d9b44b1a7349997e7e5938862' 
  AND token = 'rBOaD1EhxRNX2MXD8IDZZzZjAfpuQqed8IU9oJmksNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}