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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35b0da138b53683ca0ca929576e1e2dfd74cdd0b3e4933f7938933f10c163de2' 
  AND token = 'p4vqMEF5Xkk3BCMfTisrr8xyJten2Rlu9MWWcWf0bwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}