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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46a6aa87e622d309086b4925748592f0d123766eb077ef260510e6126a1b06e3' 
  AND token = 'PeEvMeMunOox658E1Z0klqze1Cg1R5850P+wq2aFm5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}