SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a94b689c49f7c2e5197c4de6ee098b9dc0502985ff2940744d501db9ce36313' 
  AND token = 'Lpt0nDzPCyZt7pO5R6mB/zLz6fJ9+Vevb4SuMTe4nZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}